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h have been bestowed upon it by various writers. We will therefore proceed to the few remarks which we have to make upon the three chief modes of using tobacco, viz., snuffing, smoking, and chewing. Catherine de Medicis, the personage said to have prompted the horrible massacre of St. Bartholomew's day at Paris, is commonly regarded as the inventress of snuff-taking. In Russia and Persia the penalty of death was annexed to the use of tobacco in every form except that of snuff. For this lighter offence, the punishment was softened down to simple mutilation, no greater severity being deemed necessary than that of cutting off the nose. We doubt exceedingly whether either penalty would deter the inveterate snuff-takers of the present day. Indeed, we are told somewhere that it was very common among the Persians to expatriate themselves, when they were no longer allowed to indulge in tobacco in their native country. One of the first effects of snuff is to injure the nerves of the nose, which are endowed with exquisite sensibility, and of which an incredible number are spread over the inner membrane of the nostrils. This membrane is lubricated by a secretion, which has a tendency to preserve the sense. By the almost caustic acrimony of snuff, the mucus is dried up, and the organ of smelling becomes perfectly callous. The consequence is, that all the pleasure we are capable of deriving from the olfactory organs, the _omnis copia narium_, as Horace curiously terms it, is totally destroyed. Similar effects are also produced upon the saliva, and hence it is that habitual snuff-takers are often unable to speak with proper distinctness; and the sense of taste for the same reason is very much obtunded. A snuffer may always be distinguished by a certain nasal twang--an asthmatic wheezing--and a sort of disagreeable noise in respiration, which is nearly allied to incipient snoring. Snuff also frequently occasions fleshy excrescences in the nose, which, in some instances, end in polypi. Individuals have oftentimes a predisposition to cancer in little scirrhous intumescencies, which, if kept easy and free from every thing of an irritating character, will continue harmless, but which the use of snuff sometimes frets into incurable ulcers and cancers. By the use of snuff, tumours are also generated in the throat, which obstruct deglutition, and even destroy life. Dr. Hill saw a female die of hunger, who could swallow no nourishment because
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