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that about twenty Indians have been carried off by the small-pox, on the Shiawassa, and the same number on the Flint River. Says the disease was first brought to Saginaw by Mr. Gardiner D. Williams, and it was afterwards extended to the Flint by Mr. Campau. _21st_. Rev. J. A. Agnew, of N.Y., addresses me as one of the Regents of the University, under a belief that the Board will, very soon, proceed to the election of a chancellor and professors. He takes a very just view of the importance of making it a fundamental point, to base the course of instruction on a sound morality, and of insuring the confidence of religious teachers of evangelical views, _25th_. Mr. Conner brought me, some days ago, a cranium of an Indian, named B-tow-i-ge-zhig (Both Sides of the Sun), who was killed and buried near his house in a singular way. It seems that another Indian, a young man, had fallen from a tree, and, in his descent, injured his testicles, which swelled up amazingly. Etowigezhig laughed at him, which so incensed the young fellow that he suddenly picked up a pot-hook and struck him on the skull. It fractured it, and killed him. So he died for a laugh. He was a good-natured man, about forty-five, and a good hunter. I gave the skull to Mr. Toulmin Smith, a phrenological lecturer. _26th_. Mr. Cleaveland (Rev. John) preached his farewell sermon to the First Presbyterian Church, Detroit, from Jonah iii. 2: "Arise and go to Nineveh, that great city, and preach unto it the preaching that I bid thee." This message he has faithfully and ably delivered to them for about five years that he has occupied this pulpit. _27th_. A letter of this date, from Fort Union, on the Missouri, published in the St. Louis Bulletin, gives a frightful account of the ravages of the small-pox among the Mandans, Aurickerees, Minitares and Gros Venters, of the Missouri. This disease, which first broke out about the 15th of July, among the Mandans, carried off about fifteen hundred of that tribe. It left about one hundred and thirty souls.[82] It spread rapidly, and during the autumn carried off about half of the two tribes mentioned. It was carried to the Blackfeet, Crees, and Assinaboines, who also suffered dreadfully. Upwards of one thousand of the Blackfeet perished, and about five hundred Minitares. Whole lodges were swept away, and the desolations created were frightful. [Footnote 82: The report that they were entirely extinguished was an error
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