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ure of membranous croup and its relationship to true diphtheria, that when the diagnosis between the two is uncertain the safest plan is to treat the case as one of diphtheria. In children, diphtheria may occur on the vulva, vagina, prepuce, or glans penis, and give rise to difficulty in diagnosis, which is only cleared up by demonstration of the bacillus. #Treatment.#--An attempt may be made to destroy or to counteract the organisms by swabbing the throat with strong antiseptic solutions, such as 1 in 1000 corrosive sublimate or 1 in 30 carbolic acid, or by spraying with peroxide of hydrogen. The antitoxic serum is our sheet-anchor in the treatment of diphtheria, and recourse should be had to its use as early as possible. Difficulty of swallowing may be met by the use of a stomach tube passed either through the mouth or nose. When this is impracticable, nutrient enemata are called for. In laryngeal diphtheria, the interference with respiration may call for intubation of the larynx, or tracheotomy, but the antitoxin treatment has greatly diminished the number of cases in which it becomes necessary to have recourse to these measures. Intubation consists in introducing through the mouth into the larynx a tube which allows the patient to breathe freely during the period while the membrane is becoming separated and thrown off. This is best done with the apparatus of O'Dwyer; but when this instrument is not available, a simple gum-elastic catheter with a terminal opening (as suggested by Macewen and Annandale) may be employed. When intubation is impracticable, the operation of tracheotomy is called for if the patient's life is endangered by embarrassment of respiration. Unless the patient is in hospital with skilled assistance available, tracheotomy is the safer of the two procedures. TETANUS Tetanus is a disease resulting from infection of a wound by a specific micro-organism, the _bacillus tetani_, and characterised by increased reflex excitability, hypertonus, and spasm of one or more groups of voluntary muscles. _Etiology and Morbid Anatomy._--The tetanus bacillus, which is a perfect anaerobe, is widely distributed in nature and can be isolated from garden earth, dung-heaps, and stable refuse. It is a slender rod-shaped bacillus, with a single large spore at one end giving it the shape of a drum-stick (Fig. 26). The spores, which are the active agents in producing tetanus, are highly resistant to
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