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course of a week, enough torulae to form a scum at the top and to form lees at the bottom, and to change the perfectly tasteless and entirely harmless fluid, syrup, into a solution impregnated with the poisonous gas carbonic acid, impregnated with the poisonous substance alcohol; and that, in virtue of the changes worked upon the sugar by the vital activity of these infinitesimally small plants. Now you see that this is a case of infection. And from the time that the phenomenon of fermentation were first carefully studied, it has constantly been suggested to the minds of thoughtful physicians that there was a something astoundingly similar between this phenomena of the propagation of fermentation by infection and contagion, and the phenomena of the propagation of diseases by infection and contagion. Out of this suggestion has grown that remarkable theory of many diseases which has been called the "germ theory of disease," the idea, in fact, that we owe a great many diseases to particles having a certain life of their own, and which are capable of being transmitted from one living being to another, exactly as the yeast plant is capable of being transmitted from one tumbler of saccharine substance to another. And that is a perfectly tenable hypothesis, one which in the present state of medicine ought to be absolutely exhausted and shown not to be true, until we take to others which have less analogy in their favour. And there are some diseases most assuredly in which it turns out to be perfectly correct. There are some forms of what are called malignant carbuncle which have been shown to be actually effected by a sort of fermentation, if I may use the phrase, by a sort of disturbance and destruction of the fluids of the animal body, set up by minute organisms which are the cause of this destruction and of this disturbance; and only recently the study of the phenomena which accompany vaccination has thrown an immense light in this direction, tending to show by experiments of the same general character as that to which I referred as performed by Helmholz, that there is a most astonishing analogy between the contagion of that healing disease and the contagion of destructive diseases. For it has been made out quite clearly, by investigations carried on in France and in this country, that the only part of the vaccine matter which is contagious, which is capable of carrying on its influence in the organism of the child who is vac
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