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e same thing; she believed that he must be immortal. I am sure that he never was born." [Sidenote: Two modes of action.] Two modes have been presented by which we may conceive of the influence of physical agents upon organic forms. Their long persistent action upon the individual may give rise to modifications, developing one part, stunting another; and such variations, being transmitted in an hereditary way, may become firmly fixed at last. Thus a given plant may, in the course of ages, under the influence of unremittingly acting physical conditions, undergo a permanent change, and a really new plant arise as soon as, through the repetitions of successive generations, the modifications have become so thorough, so profound, as to be capable of transmission with certainty. Perhaps this is what has taken place with many of our kitchen-garden plants, of which the special varieties may be propagated by seeds. But there is another mode by which that result may be reached, even if we decline the doctrine of St. Augustine, who, in his work "De Civitate Dei," shows how islands may be peopled with animals by "spontaneous generation." All organic forms originally spring from a simple cell, the development of which, as indicated by the final form attained, is manifestly dependent on the physical conditions it has been exposed to during its course. If those conditions change, that final form must change correspondingly; and in this manner, since all organic beings come from the same starting-point--the same cell, as has been said, which helplessly submits to whatever impression may be put upon it--the issue is the same as though a transformation or transmutation had occurred, since the descendant is not like its ancestors. Such a manner of considering these changes is in harmony with our best physiological knowledge, since it does not limit itself to a small portion of the life of an individual, but embraces its whole cycle or career. For the more complete examination of this view I may refer to the second chapter of the second book of my "Physiology." [Sidenote: Problem of the modification of forms.] But here has arisen the inquiry, Does the modification of organic forms depend exclusively on the impressions of external influences, or is it due to a nisus or force of development residing in the forms themselves? Whether we consider the entire organic series in its succession, or the progress of an individual in his developme
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