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table end. I have in my thoughts the invention of ether-inhalation and the induction of trance in mesmerism. The witch narcotised her pupils in order to produce in them delusive visions; the surgeon stupifies his patient to prevent the pain of an operation being felt. The fanatic preacher excites convulsions and trance in his auditory to persuade them that they are visited by the Holy Spirit; Mesmer produced the same effects as a means of curing disease. Let us first look into the simpler problem of ether-inhalation. It occurred to Mr Jackson, a chemist in the United States, that it might be possible, and unattended with risk, so to stupify a patient with the vapour of sulphuric ether that he might undergo a surgical operation without suffering. He communicated the idea to Mr Morton, a dentist, who carried it into execution with the happiest results. The patient became unconscious,--a tooth was extracted;--no sign of pain escaped at the time;--there was no recollection of suffering afterwards. Led by the report of this success, in the course of the autumn of 1846, Messrs Bigelow, Warren, and Heywood ventured to employ the same means in surgical operations of a more serious description. The results obtained on these occasions were not less satisfactory than the first had been. Since then, in England, France, and Germany, this interesting experiment has been repeated in numberless cases, and its general success may be considered to be established. The effects produced by the inhalation of the vapour of sulphuric ether, present a superficial resemblance to those produced by exposure to carbonic acid; but they are more closely analogous to the effects of inhaling nitrous oxide; and they may be compared and contrasted with those of opium and alcoholic liquors. But the patient is neither in the state of asphyxia, nor is he narcotised, nor drunk. The effects produced are peculiar, and deserve a name of their own. To give you a distinct idea of the ordinary phenomena of etherisation, I will cite three or four instances from a report on this subject by Dr Heyfelder, Knight, professor of medicine, and director of the surgical clinic at Erlangen. Dr Heyfelder himself, a strong and healthy man, after inhaling the vapour of ether for a minute, experienced an agreeable warmth in his whole person; after the second minute, he felt a disposition to cough, and diminution of ordinary sensibility. Then an impression supervened th
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