FREE BOOKS

Author's List




PREV.   NEXT  
|<   57   58   59   60   61   62   63   64   65   66   67   68   69   70   71   72   73   74   75   76   77   78   79   80   81  
82   83   84   85   86   87   88   89   90   91   92   93   94   95   96   97   98   99   100   101   102   103   104   105   106   >>   >|  
cases, though not constantly and in much smaller number. Tuerk has recently undertaken a very exact and thorough analysis of their occurrence in infectious diseases, in the course of which he accurately tabulated the white corpuscles in a large number of cases. The results he obtained in pneumonia are especially characteristic, for he found at the commencement of the disease that myelocytes are not seen at all or only very scantily: and it is only at the time of the crisis, or directly afterwards, that they become specially numerous. In isolated cases the increase at this time was very considerable; and in one case amounted almost to 12% of all neutrophil cells. 2. Mononuclear eosinophil cells ("=eosinophil myelocytes="). H. F. Mueller was the first to point out their importance. They constitute the eosinophil analogue of the previous group, and are much larger than the polynuclear eosinophils; medium and small sized examples are often found in leukaemia. Eosinophil myelocytes are almost constantly present in myelogenous leukaemia and in anaemia pseudolymphatica infantum. Apart from these two diseases they are very rarely found; Mendel saw them for example in a case of myxoedema, Tuerk quite exceptionally in some infectious diseases. 3. =Small neutrophil pseudolymphocytes.= They are about as large as the small lymphocytes, possess a rounded deeply stained nucleus, and a small shell of protoplasm studded with a neutrophil granulation. The relatively deep stain of the nucleus and the small share of the protoplasm in the total cell body prevent confusion with the small forms of myelocytes, which never reach such small dimensions. The neutrophil pseudolymphocytes are exceedingly infrequent, and represent products of division of the polynuclear cells; they were first described by Ehrlich in a case of hemorrhagic small-pox. The process of division goes on in the blood in such a manner that the nuclear rod first divides into two to four single nuclei, and then the whole cell splits up into as many fragments. These cells occur also in fresh pleuritic exudations. After a time the nucleus of these cells becomes free, and the little masses of protoplasm thus cut off are taken up mostly by the spleen substance. The free nucleus likewise shares in the destruction. It is of the greatest importance that these cells, which up to the present have not elsewhere been described, should receive more attention. They must be of significanc
PREV.   NEXT  
|<   57   58   59   60   61   62   63   64   65   66   67   68   69   70   71   72   73   74   75   76   77   78   79   80   81  
82   83   84   85   86   87   88   89   90   91   92   93   94   95   96   97   98   99   100   101   102   103   104   105   106   >>   >|  



Top keywords:
neutrophil
 
myelocytes
 
nucleus
 
protoplasm
 

eosinophil

 

diseases

 

division

 

constantly

 

polynuclear

 

importance


leukaemia

 

present

 

pseudolymphocytes

 

number

 

infectious

 

hemorrhagic

 

studded

 
process
 
Ehrlich
 

infrequent


represent

 

manner

 
exceedingly
 

granulation

 

dimensions

 

products

 
prevent
 

confusion

 

likewise

 
shares

destruction

 
substance
 

spleen

 

greatest

 
attention
 

significanc

 

receive

 

splits

 

nuclei

 

single


divides

 
fragments
 
masses
 

exudations

 

pleuritic

 

nuclear

 

pseudolymphatica

 

directly

 

specially

 
crisis