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fts from one hind foot to the other, stamps, kicks at the belly, frequently looks anxiously at its flank, moans plaintively, lies down and quickly gets up again, grinds its teeth, twists its tail, and keeps the back habitually arched and rigid and the hind feet advanced under the belly. The bowels may be costive and the feces glistening with a coat of mucus, or they may be loose and irritable, and the paunch or even the bowels may become distended with gas (bloating) as the result of indigestion and fermentation. In some animals, male and female alike, the rigid, arched condition of the back will give way to such undulating movements as are sometimes seen in the act of coition. The disease does not always appear in its full severity; for a day, or even two, however, there may be merely loss of appetite, impaired rumination, a disposition to remain lying down, yet when the patient is raised it manifests suffering by anxiously looking at the flanks, shifting or stamping of the hind feet, shaking of the tail, and attempts to urinate, which are either fruitless or lead to the discharge of a small quantity of high-colored or perhaps bloody urine. In some recent slight cases, and in many chronic ones, these symptoms may be absent or unobserved, and an examination of the urine is necessary to reach a safe conclusion. The urine may contain blood, or it may be cloudy from contained albumin, which coagulates on heating with nitric acid (see "Albuminuria," p. 121); it may be slightly glairy from pus, or gritty particles may be detected in it. In seeking for casts of the uriniferous tubes, a drop may be taken with a fine tube from the bottom of the liquid after standing, and examined under a power magnifying 50 diameters. If the fine, cylindroid filaments are seen they may then be examined with a power of 200 or 250 diameters. (Pl. XI, fig. 5.) The appearance of the casts gives some clue to the condition of the kidneys. If made up of large, rounded or slightly columnar cells, with a single nucleus in each cell (epithelial), they imply comparatively slight and recent disease of the kidney tubes, the detachment of the epithelium being like what is seen in any inflamed mucous surface. If made up largely of the small, disk-shaped and nonnucleated red blood globules, they imply escape of blood, and usually a recent injury or congestion of the kidney--it may be from sprains, blows, or the ingestion of acrid or diuretic poisons. If the
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