fever, pain and tenesmus disappear,
and the patient wakes with a feeling of health. If this should not take
place in three hours, owing to the more advanced state of the disease,
another dose of Apis is required, after which the patient soon feels
well.

If the dysenteric disease has had a chance to localize itself, and to
assume a higher degree of intensity, it becomes necessary to excite the
organic reaction all the more frequently. Under these circumstances we
repeat the medicine every hour, or every two or three hours, one globule
at a time, until all further medication has become unnecessary.

It is well known that epidemic diarrh[oe]a, viz., a diarrh[oe]a
resulting from peculiar alterations of the normal condition of the
atmosphere, earth, water, indispensable food, or from other still
unknown elementary influences inevitably acting upon every body,
commences in the form of a simple, apparently unimportant diarrh[oe]a;
that it gradually increases in intensity as the processes of nutrition
and sanguification become more deeply disturbed, and that it finally
terminates in life-destroying cholera. All these different stages of
diarrh[oe]a, whether with or without vomiting, watery or papescent, of
one color or another, with or without pain, with or without fever, have
yielded readily, safely and thoroughly to Apis in my hands. I must
except, however, cholera of the epidemic form, where I have not yet been
able to try Apis for want of opportunity. As far as my personal
observations go, I am disposed to affirm that the best mode of effecting
a good result, is to give Apis 3 and Aconite 3, in alternation, one drop
of each preparation well shaken in a bottle containing twelve
tablespoonfuls of water, and giving a tablespoonful every hour or three
hours, if the danger is great, and in milder cases a full drop
alternately morning and evening. This treatment is continued until an
improvement sets in, after which the organic reaction is permitted to
develope itself, which will terminate in a few hours or days, according
as the disease is more or less violent, and assistance was sought more
or less early, in the perfect recovery of the patient.

This end is not always attained with equal certainty and rapidity, if
Apis is not given in alternation with Aconite. In such a case, Apis
alone often develops a powerful reaction, which is avoided by the
alternate use of Aconite. Wherever the case is urgent, and it is
important to