rendered less dangerous by this means.

But if the disease sets in with a considerable degree of intensity at
the very outset, and the fever continues without abatement, it is
advisable to keep up a medicinal impression by repeating the dose. To
this end we dissolve a globule of Apis 30, in seven dessert-spoonfuls of
water, by shaking the solution vigorously in a corked vial, and giving a
dessert-spoonful every three, six, or twelve hours as the case may
require. In all ordinary cases a single solution of this kind sufficed
to subdue the fever and to secure a favorable termination of the
disease.

The struggle between disease and medicine assumes a far different form,
if the morbific poison has penetrated the organism more deeply; if a
process of disorganization has already developed itself in the
intestinal mucous membrane, and if the alteration of the sanguineous
fluid, which is an inherent accompaniment of such a disorganizing
process, has depressed the nervous activity to such a degree that
typhus, or paralysis of the brain or lungs seems unavoidable, as may be
inferred from the bright-red tongue, which is thickly studded with
eruptive vesicles, and speedily becomes excoriated, fissured and covered
with aphthae; by a copious discharge of thick, white, bloody and fetid
mucus from the nose; by the swelling and induration of the parotid
glands, increasing difficulty of deglutition; sensitiveness of the
abdomen to pressure; badly-colored, slimy, bloody diarrh[oe]a; scanty
emissions of turbid, red, painful urine; accelerated and labored
breathing; loss of consciousness; delirium; sopor; convulsions;
trembling of the limbs; appearance as if the patient were lying in his
bed in a state of fainting; the skin is at times burning, hot and dry;
at others it feels like parchment, cooler; at others again, hot and cool
together in spots; the fever increases with changing pulse, and is more
constant; in short, all the symptoms, although developing themselves
less rapidly, show that a fatal termination becomes more and more
probable. In such a case it is above all things necessary to saturate
the organism with Apis. If there is much fever, this result is best
accomplished by means of alternate doses of Aconite and Apis, a few
drops of the third potency, shaken together with twelve tablespoonfuls
of water, each drug by itself, the dose to be repeated every hour; and
if the temperature is rather depressed, by giving Apis without th