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lobe and provinces from one another; leads one stream to another and discharges them upon a sandy desert, changed thereby into smiling meadow; three quarters of the globe he plunders and transplants them into a fourth. Even climate, air, and weather acknowledge his sway. While he roots out forests and drains the swamp, the heaven grows clear above his head, moisture and mist are lost, winter becomes milder and shorter, because rivers are no longer frozen over." And the mind of man is refined with the refining of his clime. The state occupies the citizen in the necessities and comforts of life. Industry gives the state security and rest from without; from within, granting to thinker and artist that fruitful leisure through which the age of Augustus came to be called the Golden Age. The arts now take a more daring and untrammelled flight, science wins a light pure and dry, natural history and physical science shatter superstition, history extends a mirror of the times that were, and philosophy laughs at the follies of mankind. But when luxury grows into effeminacy and excess, when the bones begin to ache, and the pestilence to spread and the air becomes infected, man hastens in his distress from one realm of nature to another, that he may at least find means for lessening his pains. Then he finds the divine plant of China; from the bowels of the earth he digs out the mightily-working mercury, and from the poppy of the East learns to distil its precious juice. The most hidden corners of nature are investigated; chemistry separates material objects into their ultimate elements, and creates worlds of her own; alchemists enrich the province of physical science; the microscopic glance of a Schwammerdam surprises nature in her most secret operations. Man goes still further; necessity or curiosity transcends the boundaries set by superstition: he seizes the knife, takes courage, and the masterpiece of nature is discovered, even man. Thus did it behoove the least, the poorest, to help us to reach the highest; disease and death must lend their aid to man in teaching him Gnothi seauton ("Know thyself!"). The plague produced and formed our Hippocrates, our Sydenhams, as war is the mother of generals; and we owe to the most devastating disease that ever visited humanity an entire reformation of our medical system. Our intention was to show the influence upon the perfecting of the soul through the temperate enjoyment of the pleasure
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