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rapidly taking a foremost place. Of its practical achievements in connexion with disease, and with the part played by bacteria and other minute organisms in the life and affairs of man, it is not necessary to speak. Every one knows the great advances that have been made in recent years in identifying (and to a less extent in controlling) disease-producing organisms, whether bacteria, protozoa (such as the organisms causing malaria, dysentery, etc.), or more highly organized parasites. The attempt, however, to combat these pathogenic bacteria has led to discoveries of the highest importance with regard to the production of immunity, not only against specific germs, but against many organic poisons such as snake venom and various vegetable toxins. That an attack of certain diseases leaves the patient immune to that disease for a longer or shorter time has of course been known for centuries, but it is a modern discovery that a specific poison induces the body to produce a specific antidote which neutralizes it, and the detailed working out of this principle and the study of the means by which the immunity is brought about promise to lead us a long way towards the central problem of the nature and activities of life itself. We have seen how zoology has been led back into physiological channels of research, and how the study of bacteria is opening up some of the deepest problems of the reaction of living things to environmental stimuli, and just as the various branches of these sciences interlace and influence one another, so all of them, in recent years, have been coming into contact with the inorganic sciences of chemistry and physics. One of the noteworthy features of science in all its branches in recent years has been the tendency of subjects which were at one time regarded as distinct to come together again and to find that the problems of each can only be successfully attacked by the co-operation of the others. In their earlier days the biological sciences were in most respects far removed from chemistry and physics; it was recognized, of course, that organisms were in one sense at least physico-chemical mechanisms, consisting of chemical elements and subject to the fundamental laws of matter and energy. With the advent of the theory of evolution this conception of the organism as a mechanism took more definite shape, and among many biologists the belief was held that in no very long time all the phenomena of life w
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