e lean,
sour, haggard dyspeptic, whose gnawing stomach has long ago eaten every
smile from his face and every muscle from his body. See his appetite
return, and with it his health; see the new man. See her that was
radiant with health and loveliness bloated and too early withering away;
want of exercise or mental anguish, or some lurking disease has deranged
the internal organs of digestion, assimilation, or secretion till they
do their ill. Her blood is vitiated, her health is gone. Give her these
PILLS to stimulate the vital principle into renewed vigor, to cast out
the obstructions, and infuse a new vitality into the blend. Now look
again--the roses blossom on her cheek, and where lately sorrow sat joy
bursts from every feature. See the sweet infant wasted with worms. Its
wan, sickly features tell you without disguise, and painfully distinct,
that they are eating its life away. Its pinched-up nose and ears and
restless sleepings tell the dreadful truth in language which every
mother knows. Give it the PILLS in large doses to sweep these vile
parasites from the body. Now turn again and see the ruddy bloom of
childhood. Is it nothing to do these things? Nay, are they not the
marvel of this age? And yet they are done around you every day.

Have you the less serious symptoms of these distempers, they are the
easier cured. Jaundice, Costiveness, Headache, Sideache, Heartburn. Foul
Stomach, Nausea, Pain in the Bowels, Flatulency, Loss of Appetite,
King's Evil, Neuralgia, Gout, and kindred complaints all arise from the
derangements which these PILLS rapidly cure. Take them perseveringly,
and under the counsel of a good physician if you can; if not take them
judiciously by such advice as we give you, and the distressing dangerous
diseases they cure, which afflict so many millions of the human race,
are cast out like the devils of old--they must burrow in the brutes and
in the sea.

Prepared by DE. J. C. AYER, & CO.,
PRACTICAL AND ANALYTICAL CHEMISTS,
LOWELL, MASS.,

[Illustration] And Sold by all Druggists.[Illustration]

* * * * *

THE ANNUAL CYCLOPAEDIA

AND

REGISTER OF IMPORTANT EVENTS,

OF THE YEAR 1861:

EMBRACING

POLITICAL, CIVIL, MILITARY, AND SOCIAL AFFAIRS; PUBLIC DOCUMENTS;
BIOGRAPHY; STATISTICS; COMMERCE; FINANCE; LITERATURE; SCIENCE;
AGRICULTURE, AND MECHANICAL INDUSTRY.

This is a Cyclopaedia of what took place during the year 1861. It
comprises not on