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of arsenicalis is to be increased half-a-drop each day, and in the latter instance one drop daily is to be the advance; the quantity in both cases to be distributed over three doses, one to be given in the morning, one at noon, and the last at night. The medicine is to be kept on increasing each day, until the dog loathes his food; has a running from the eyes; a scarlet conjunctiva; or exhibits some symptom that denotes the physic has hold of his system; when the arsenicalis is to be discontinued for three days, and then steadily persevered with at the dose which preceded the derangement. Thus, supposing it requires three and a half drops to throw the small dog off his appetite, the quantity to resume with will in that case be three drops. There is no power I possess which can predicate the quantity of the liquor arsenicalis which an animal will bear; its effects on different creatures of the same species are so various, that what one can gorge with impunity would kill his companion. On this account no fixed quantity of the medicine can be recommended; but the practitioner must be satisfied to watch the symptoms induced, and be content to be guided by these. So soon as the physiological symptom is beheld, the good results of the medicine may be anticipated; and no compound in the pharmacopoeia works with greater certainty. The disease will begin to decline; and in a month, six weeks, or two months at furthest, will be thoroughly eradicated. In the course of that period, however, it may be as well to give Nature a jolt every now and then, by occasionally increasing the dose, being always prepared to diminish it on the symptoms giving the slightest hint that it is prudent so to do. The arsenicalis should be used simply diluted with water; and during the period occupied by the cure, no other medicine whatever will be required. The next form of mange attacks very fat and cruelly overfed animals. The poor dog is very foul. He, as it were, smells aloud; and his hide is enormously thickened, being everywhere devoid of sensation. Pinch it as hard as you can--even until the moisture be forced through the pores by the pressure--and the operation which should inflict pain, will only communicate pleasure. The animal, instead of crying out or endeavoring to snap, will stand altogether quiet, the expression of the face announcing the perfect delight it experiences; or the head turns round to lick the hand of the pincher, the
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