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ng had a very bad small-pox of the confluent sort." This is the first use of the word _vaccination_, or, more familiarly, cow-pox, which is an eruption arising from the insertion into the system of matter obtained from the eruption on the teats and udders of cows, and especially in Gloucestershire; it is also frequently denominated _vaccine matter_; and the whole affair, inoculation and its consequences, is called vaccination, from the Latin _vacca_, a cow. It is admitted that Jenner's merit lay in the scientific application of his knowledge of the fact that the chapped hands of milkers of cows sometimes proved a preventive of small-pox, and from those of them whom he endeavored to inoculate resisting the infection. These results were probably known far beyond Jenner's range, and long before his time; for we have respectable testimony of their having come within the observation of a Cheshire gentleman, who had been informed of them shortly after settling on his estate in Prestbury parish, in or about 1740. This does not in the least detract from Jenner's merit, but shows that to his genius for observation, analogy, and experiment, we are indebted for this application of a simple fact, only incidentally remarked by others, but by Jenner rendered the stepping-stone to his great discovery--or, in other words, extending its benefits from a single parish in Gloucestershire to the whole world. We agree with a contemporary, that, "among all the names which ought to be consecrated by the gratitude of mankind, that of Jenner stands pre-eminent. It would be difficult, we are inclined to say impossible, to select from the catalogue of benefactors to human nature an individual who has contributed so largely to the preservation of life, and to the alleviation of suffering. Into whatever corner of the world the blessing of printed knowledge has penetrated, there also will the name of Jenner be familiar; but the fruits of his discovery have ripened in barbarous soils, where books have never been opened, and where the savage does not pause to inquire from what source he has derived relief. No improvement in the physical sciences can bear a parallel with that which ministers in every part of the globe to the prevention of deformity, and, in a great proportion, to the exemption from actual destruction." The ravages which the small-pox formerly committed are scarcely conceived or recollected by the present generation. An instance of
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