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applications; this plan of treatment is prejudicial. "The most proper time for the removal of families to this country from the Atlantic states, is early in the spring, while the rivers are full; or if the journey be made by land, as soon as the roads are sufficiently settled, and the waters abated. "Persons unaccustomed to the climate of the lower Mississippi country, are necessarily exposed, whilst there in the summer season, to many causes of disease. It will be advisable for such to have a prudent care of their health, and yet, a care distinct from that finical timidity which renders them liable to early attacks of sickness. "There is one important consideration, which perhaps has been somewhat overlooked by medical men, who have written on this subject. Natives of colder and healthier regions, when exposed in southern and sickly climates, experience, if they remain any length of time without evident and violent disease, an alteration in the condition of the liver, and of the secreted bile itself; when it passes through the bowels, its color being much darker than usual. Sometimes, indeed, it appears to be "locked up in the liver," the stools having an ashen appearance. This state of the biliary secretion is frequently accompanied, although the patient is otherwise apparently in tolerable health, by a pain over the eye-balls, particularly when the eyes are rolled upward. "The proper mode of treatment for such symptoms is, to take without delay, not less than twenty grains of calomel, and in eight hours a wine glass full of castor oil. The tone of the stomach should not be suffered to sink too much after the operation of the medicine, which, if necessary, may be repeated in twenty-four hours. Sulphate of quinine, or other tonics, with nutritive food, which is easy of digestion, should also be taken in moderate portions at a time. "Where diseases are rapid in their progress, and dangerous, no time is to be lost. The practice of taking salts and other aperients, when in exposed situations, and for the purpose of preventing disease, is injurious. It is sufficient, that the bowels be kept in a natural and healthy state; for all cathartics, even the mildest, have a tendency to nauseate the stomach, create debility, and weaken the digestive faculty. A reduction of tone in the system, which is always advantageous, will be more safely effected by using somewhat less than usual of animal food, and of spirituous, st
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