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ther, with the hair at the root of the nose so prominent as to constitute a separate bridge known as the nasal brow. The size of the pupil, and its humidity, which have so much to do with the expression of the eye, vary directly with the activities of the driving and checking divisions of the vegetative system, and are a pretty good index as to which, at the time of observation, is predominant. When the check system is in control, the pupils are large and dilated. When its antagonist and rival, the drive system, is on top, the pupils are small and contracted. The reactions of the pupils when charged by strong emotion, like fear or anger, likewise turn upon the status of check or drive internal secretions in the economy of the organism at the time the exciting agent presents itself. MUSCLES It would seem, at first sight, that organs like muscles, mechanical instruments for the manipulation of the organism in space, would be more or less independent of the subtler processes of internal chemistry of the blood and tissues. But no assumption would be more beside the mark. Just as much as the bones and viscera, the teeth and the hair, they show grossly how they are being influenced by all the endocrine glands. So thyroid types generally have a skeleton sparsely covered with a muscular mantle. Pituitary types have large well-developed muscles. The pineal gland has some definite relation to muscle chemistry not yet probed. Thus, it has been shown that when the pineal has been completely destroyed prematurely by lime deposits in it, there is concomitant a wasting of muscles in places. This waste is sometimes replaced by fat. Pictures and images in wood and stone of these muscle freaks dating from the fifteenth, sixteenth, and seventeenth century are in existence. Then there is the extraordinary fatigability of the muscles which occurs in the thymus types, who nevertheless have large well-rounded muscles, a paradox of contradiction between anatomy and physiology. Such a type, for instance, may be picked out by a football coach for an important position in a line-up, simply on the tremendous impressiveness of the muscle make-up, only to see him bowled over and out in the first scrimmage. The tone of muscles, the quality of resisting firmness or yielding softness, is essentially determined by the adrenal glands, especially in time of stress and strain. Brown-Sequard was the first to show that extracts of sex glands could inc
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