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ese authors for his inability to convince himself of the validity of their claims at the present moment. He thinks that only continued breeding of these apparent mutants through several generations can afford convincing evidence that we are here dealing with mutants rather than with merely pathological variations. What was said in regard to the production of new species by physico-chemical means may be repeated with still more justification in regard to the second problem of transformation, namely the making of living from inanimate matter. The purely morphological imitations of bacteria or cells which physicists have now and then proclaimed as artificially produced living beings; or the plays on words by which, e.g. the regeneration of broken crystals and the regeneration of lost limbs by a crustacean were declared identical, will not appeal to the biologist. We know that growth and development in animals and plants are determined by definite although complicated series of catenary chemical reactions, which result in the synthesis of a DEFINITE compound or group of compounds, namely, NUCLEINS. The nucleins have the peculiarity of acting as ferments or enzymes for their own synthesis. Thus a given type of nucleus will continue to synthesise other nuclein of its own kind. This determines the continuity of a species; since each species has, probably, its own specific nuclein or nuclear material. But it also shows us that whoever claims to have succeeded in making living matter from inanimate will have to prove that he has succeeded in producing nuclein material which acts as a ferment for its own synthesis and thus reproduces itself. Nobody has thus far succeeded in this, although nothing warrants us in taking it for granted that this task is beyond the power of science. XV. THE VALUE OF COLOUR IN THE STRUGGLE FOR LIFE. By E.B. Poulton. Hope Professor of Zoology in the University of Oxford. INTRODUCTION. The following pages have been written almost entirely from the historical stand-point. Their principal object has been to give some account of the impressions produced on the mind of Darwin and his great compeer Wallace by various difficult problems suggested by the colours of living nature. In order to render the brief summary of Darwin's thoughts and opinions on the subject in any way complete, it was found necessary to say again much that has often been said before. No attempt has been made to displ
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