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uefaction which result in the formation of cystic cavities in the interior of the tumour. The colour depends on the amount of blood in the tumour, and on the presence of the products of degeneration. The blood vessels are usually represented by mere chinks or spaces between the cells. This peculiarity accounts for the facility with which haemorrhage takes place into the substance of the tumour, the persistence of the bleeding when it is incised or ulcerates through the skin, and the readiness with which the sarcomatous cells are carried off and infect distant parts through the blood-stream. Sarcomas are devoid of lymphatics, and unless originating in lymphatic structures--for example, in the tonsil--they rarely infect the lymph glands. Minute portions of the tumour grow into the small veins, and, becoming detached, are transported by the blood-current to distant organs, where they are arrested in the capillaries and give rise to secondary growths. These are most frequently situated in the lungs, except when the primary growth lies within the territory of the portal circulation, in which case they occur in the liver. The secondary growths closely resemble the parent tumour. Sarcoma may invade an adjacent vein on such a scale that if the invading portion becomes detached it may constitute a dangerous embolus. This may be observed in sarcoma of the kidney, the growth taking place along the renal vein until it projects into the vena cava. [Illustration: FIG. 55.--Recurrent Sarcoma of Sciatic Nerve in a woman aet. 27. Recurrence twenty months after removal of primary growth.] In its growth, a sarcoma compresses and destroys neighbouring parts, surrounds vessels and nerves, and may lead to destruction of the skin, either by invading it, or more commonly by causing sloughing from pressure. Inflammatory and suppurative changes may take place as a result of pyogenic infection following upon sloughing of the overlying skin or upon an exploratory incision. Once the skin is broken the tumour fungates through the opening. Sarcomas vary in malignancy, especially as regards rapidity of growth and capacity for dissemination. Certain of them, such as the so-called "recurrent fibroid of Paget," grow comparatively slowly, and are only malignant in the sense that they tend to recur locally after removal; others--especially the more cellular ones--grow with extreme rapidity, and are early disseminated throughout the body, resembling in
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