iple subcutaneous tumours (cf. Fig. 49).

(Sir H. J. Stiles' case.)]

#Zanthoma# is a rare but interesting form of tumour, composed of a
fibrous and fatty tissue, containing a granular orange-yellow pigment,
resembling that of the corpus luteum. It originates in the corium and
presents two clinical varieties. In the first of these, it occurs in the
form of raised yellow patches, usually in the skin of the eyelids of
persons after middle life, and in many instances is associated with
chronic jaundice; the patches are often symmetrical, and as they
increase in size they tend to fuse with another.

The second form occurs in children and adolescents; it may affect
several generations of the same family, and is often multiple, there
being a combination of thickened yellow patches of skin and projecting
tumours, some of which may attain a considerable size (Figs. 48 and 49).
On section, the tumour tissue presents a brilliant orange or saffron
colour.

There is no indication for removing the tumours unless for the deformity
which they cause; exposure to the X-rays is to be preferred to
operation.

[Illustration: FIG. 49.--Zanthoma showing Subcutaneous Tumours on
Buttocks. From same patient as Fig. 48.]

#Chondroma.#--A chondroma is mainly composed of cartilage. Processes of
vascular connective tissue pass in between the nodules of cartilage
composing the tumour from the fibrous capsule which surrounds it. On
section it is of a greyish-blue colour and semi-translucent. The tumour
is firm and elastic in consistence, but certain portions may be densely
hard from calcification or ossification, while other portions may be
soft and fluctuating as a result of myxomatous degeneration and
liquefaction. These tumours grow slowly and painlessly, and may surround
nerves and arteries without injuring them. They may cause a deep hollow
in the bone from which they originate. All intermediate forms between
the innocent chondroma and the malignant chondro-sarcoma are met with.
Chondroma may occur in a multiple form, especially in relation to the
phalanges and metacarpal bones. When growing in the interior of a bone
it causes a spindle-shaped enlargement of the shaft, which in the case
of a phalanx or metacarpal bone may resemble the dactylitis resulting
from tubercle or syphilis. A chondroma appears as a clear area in a
skiagram.

A _skiagram_ of a bone in which there is a chondroma shows a clear
rounded area in the position of the tu