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all into shape. My sponsor and I had some pretty good sessions about it, and some of the screwy results I wrote you begin to make sense. I had the good luck to talk to an outstanding man in the field of nucleic acid synthesis and he was quite enthusiastic about the caliber of our work. He feels quite strongly--but has no real evidence--that the synthesis of both types of nucleic acid are independent of each other and has pointed out some significant references that I did not know about. I'm anxious to buckle down and really lick this nucleic acid problem ... in time for a June degree. Cordially, Jonathan P.S. Please send me a reprint of your lecture on "Memory Banks--Transistorized Neurones." The lecture was ingenious, but there are some biological phenomena with which I don't agree. Remember, I'm the biologist. Honestly, Doc, don't you think--_entre nous_--that your idea that a living organism, can be compared with automata in picking up informational items and processing them simultaneously in parallel, rather than in series, is naif? J. * * * * * October 28, 1958 Dr. R. Von Engen, Journal of the National Academy of Sciences, Washington, D. C. Dear Dr. Von Engen: I apologize for not answering your letter sooner. I assume you were pulling my leg when you suggested that I make a science-fiction story out of "the confused ideas of a beginning graduate student." You might give _your_ idea of a "possible science-fiction story" to one of your acolytes that has some small experience in the field of writing--not science. I am afraid that your other suggestions are not germane to the problem of nucleic acid synthesis and metabolism, a problem that has been occupying _all_ my time. In fact, I've been doing with three to four hours of sleep these days. With the kind of concentration that I can offer the problem, there is no question that the data are falling into line, and our research is going rather well. We will show, I hope, fairly conclusively that there is little or no interconversion between the two types of nucleic acid synthesis in the cell. Despite your ingenious mathematical approaches for stimulation criteria, in biological research--a very abstruse field--even your multiplex machines with elaborate means of intercommunication are not sophisticated enough--or ever will be--to cope with the complexities inherent in the numerous interacting biosyntheses on the
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