eriment.

In summing up their results at the conclusion of this report the
following statement is made:

Out of a total or eighteen nonimmunes whom we have inoculated with
contaminated mosquitoes, since we began this line of investigation,
eight, or 44.4 per cent, have contracted yellow fever. If we exclude
those individuals bitten by mosquitoes that had been kept less than
twelve days after contamination, and which were therefore probably
incapable of conveying the disease, we have to record eight positive and
two negative results--80 per cent.

In a still later report (May, 1901) Dr. Reed says, "We have thus far
succeeded in conveying yellow fever to twelve individuals by means of
the bites of contaminated mosquitoes."

The nonimmune individuals experimented upon were all fully informed as
to the nature of the experiment and its probable results and all gave
their full consent. Fortunately no one of these brave volunteers in the
cause of science and humanity suffered a fatal attack of the disease,
although several were very ill and gave great anxiety to the members of
the board, who fully appreciated the grave responsibility which rested
upon them. That these experiments were justifiable under the
circumstances mentioned is, I believe, beyond question. In no other way
could the fact established have been demonstrated, and the knowledge
gained is of inestimable value as a guide to reliable measures of
prevention. Already it is being applied in Cuba, and without doubt
innumerable lives will be saved as a result of these experiments showing
the precise method by which yellow fever is contracted by those exposed
in an "infected locality." Some of these volunteers were enlisted men of
the United States Army and some were Spanish immigrants who had recently
arrived in Cuba. When taken sick they received the best possible care,
and after their recovery they had the advantage of being "immunes" who
had nothing further to fear from the disease which has caused the death
of thousands and tens of thousands of Spanish soldiers and immigrants
who have come to Cuba under the orders of their government or to seek
their fortunes.

The experiments already referred to show in the most conclusive manner
that the blood of yellow fever patients contains the infectious agent,
or germ, to which the disease is due, and this has been further
demonstrated by direct inoculations from man to man. This experiment was
made by Dr. Reed at "Ca