ore, but a week after the mosquito's bite he came down with the
disease. It has also been noted that in such parts of the country as
Greenland and Alaska, where mosquitoes are as thick as in the far-famed
New Jersey marshes, malaria does not result from the mosquito bites
unless a malaria patient from other countries starts the infection.

The disease itself may be mild or severe. It takes about a week after
the mosquito bites before the symptoms appear, and sometimes the attack
is postponed for weeks or months. Chills are the usual accompaniment of
the disease; in children under six, convulsions are more common. The
chill lasts from a few minutes to an hour, and directly after the chill
comes the fever, which lasts three or four hours. The attacks usually
occur every other day and sometimes every two days, generally at the
same time of day. When persons have lived for a long time in malarial
regions, the intermittency of the chill and fever is less noticeable and
the continuous character of the fever often leads the disease to be
mistaken for typhoid. The intermittent regularity of the fever, however,
although between attacks the temperature never falls to normal,
distinguishes this type of malarial fever from true typhoid. The
positive determination of the disease is possible by an examination of
the patient's blood, in which the malarial parasite can readily be
found. Quinine is the remedy and the only remedy, and, fortunately, it
does no harm, even before the character of the disease is positively
known. The chill seems to be due to the development of a new brood of
parasites in the blood of the malarial patient, and in order that the
quinine shall have its effect on the blood, it must be swallowed three
or four hours before the time of the expected chill, and then it will
probably prevent, not the next chill but the one after. If the quinine
cannot be taken directly with reference to an expected chill, then it
must be taken regularly, sometimes for months before the chills cease.

_Yellow fever._

Yellow fever, although not common in this country, is interesting as
being almost exactly similar in its mode of infection to malaria. It is
transmitted through a parasite, as is malaria, and can only be passed
along through the agency of another kind of mosquito, known as
stegomyia. In 1899 there was a serious outbreak of this pestilence in
the cities of our southern coast, and the terrors of the plague of the
Middle A