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eposit of fat takes place (though less in amount), which commences at the loins. This is the first sign of puberty. In the change of life the first sign is visible at the lower part of the back of the neck, on a level with the bones known as the two lowest cervical vertebrae. Here commences an accumulation of fat, which often grows to form two distinct prominences, and is an infallible index of the period of a woman's life. The breasts do not partake of this increase, but become flat and hard, the substance of the gland losing its spongy structure. The legs and arms lose their roundness of outline, and, where they do not grow fat, dry up, and resemble those of the other sex. The abdomen enlarges, even to the extent occasionally of leading the wife to believe that she is to be a mother,--a delusion sometimes strengthened by the absence of the monthly sickness. Finally, a perceptible tendency to a beard at times manifests itself, the voice grows harder, and the characteristics of the female sex become less and less distinct. Some who are more fortunate than their neighbours do not experience the least discomfort at the change of life. They simply note that at the expected time the illness does not appear, and for ever after they are free from it. These are the exceptions. More commonly, marked alterations in the health accompany this important crisis, and call for sedulous hygienic care. It is gratifying to know that nearly all these threatening affections can be avoided by such care, as they depend upon causes under the control of the individual. Another fact, to which we have already referred, is full of consolation. It is an unexpected fact--one that we should hardly credit, did it not rest on statistical evidence of the most indisputable character. The popular opinion, every one knows, is, that the period of the change of life is one peculiarly dangerous to women. If this is so, we might expect that, if the number of deaths between the ages of forty and fifty years in the two sexes be compared, we should find that those of females far exceed those of males. This is, however, not the case. On the contrary, the deaths of the males exceed in number those of the females. Hasty readers may draw a false conclusion from this statement. They may at once infer that the change of life merits little or no attention, if it thus in nowise increases the bills of mortality. This would be a serious error. All intelligent physici
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