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obbes of Malmesbury, his contemporary, said of him, "He is the only man, perhaps, that ever lived to see his own doctrine established in his lifetime." In one important respect Harvey's account of the circulation was incomplete. He knew nothing of the vessels which we now speak of as capillaries. Writing to Paul Marquard Slegel, of Hamburg, in 1651, he says, "When I perceived that the blood is transferred from the veins into the arteries through the medium of the heart, by a grand mechanism and exquisite apparatus of valves, I judged that in like manner, wherever transudation does not take place through the pores of the flesh, the blood is returned from the arteries to the veins, not without some other admirable artifice" (_non sine artificio quodam admirabili_). It was this _artificium admirabile_ of which Harvey was unable to give a description. On account of the minuteness of their structure, the capillaries were beyond his sight, aided as it was by a magnifying glass merely. He indeed demonstrated physiologically the existence of some such passages; but it remained for a later observer, with improved appliances, to verify the fact. This was done by Malpighi in 1661, who saw in the lung of a frog, which was so mounted in a frame as to be viewed by transmitted light, the network of capillaries which connect the last ramifications of the arteries with the radicles of the veins. Harvey rightly denied that the arteries possessed any pulsific power of their own, and maintained that their pulse is owing solely to the sudden distension of their walls by the blood thrown into them at each contraction of the ventricles. But the remission which succeeds the pulse was regarded by him as caused simply by collapse of the walls of the arteries due to elastic reaction. Knowing nothing of the muscular coat of the arteries, he was unaware of the fact that the elastic reaction of the arteries, after their distension, is aided by the tonic contractility of their walls; the two forces, physical and vital, acting in concert with each other--the former converting the intermittent flow from the heart into an even stream in the capillaries and veins; the latter, through the vaso-motor system, regulating the flow of blood to particular parts in order to meet changing requirements. It is somewhat surprising to find that such an accurate observer as Harvey should have failed to recognize the significance and importance of the system of l
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