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I can not conceive. It was practiced by the Bakwains at a time when they had no intercourse, direct or indirect, with the southern missionaries. They all adopt readily the use of vaccine virus when it is brought within their reach. A certain loathsome disease, which decimates the North American Indians, and threatens extirpation to the South Sea Islanders, dies out in the interior of Africa without the aid of medicine; and the Bangwaketse, who brought it from the west coast, lost it when they came into their own land southwest of Kolobeng. It seems incapable of permanence in any form in persons of pure African blood any where in the centre of the country. In persons of mixed blood it is otherwise; and the virulence of the secondary symptoms seemed to be, in all the cases that came under my care, in exact proportion to the greater or less amount of European blood in the patient. Among the Corannas and Griquas of mixed breed it produces the same ravages as in Europe; among half-blood Portuguese it is equally frightful in its inroads on the system; but in the pure Negro of the central parts it is quite incapable of permanence. Among the Barotse I found a disease called manassah, which closely resembles that of the 'foeda mulier' of history. Equally unknown is stone in the bladder and gravel. I never met with a case, though the waters are often so strongly impregnated with sulphate of lime that kettles quickly become incrusted internally with the salt; and some of my patients, who were troubled with indigestion, believed that their stomachs had got into the same condition. This freedom from calculi would appear to be remarkable in the negro race, even in the United States; for seldom indeed have the most famed lithotomists there ever operated on a negro. The diseases most prevalent are the following: pneumonia, produced by sudden changes of temperature, and other inflammations, as of the bowels, stomach, and pleura; rheumatism; disease of the heart--but these become rare as the people adopt the European dress--various forms of indigestion and ophthalmia; hooping-cough comes frequently; and every year the period preceding the rains is marked by some sort of epidemic. Sometimes it is general ophthalmia, resembling closely the Egyptian. In another year it is a kind of diarrhoea, which nothing will cure until there is a fall of rain, and any thing acts as a charm after that. One year the epidemic period was marked by a di
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