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the body, and is then easily transferred to the cow, if the same man grooms and dresses the horse and milks the cow. It may also appear in the cow by infection, more or less direct, from a person who has been successfully vaccinated. Many believe that it is only a form of the smallpox of man modified by passing through the system of cow or horse. It is, however, unreasonable to suppose that this alleged modified smallpox could have been transmitted from child to child (the most susceptible of the human race) for 90 years, under all possible conditions, without once reverting to its original type of smallpox. Chauveau's experiments on both cattle and horses with the virus of smallpox and its inoculation back on the human subject go far to show that in the climate of western Europe, at least, no such transformation takes place. Smallpox remains smallpox and cowpox, cowpox. Again, smallpox is communicable to a person who visits the patient in his room but avoids touching him, while cowpox is never thus transferred through the air unless deliberately diffused in the form of spray. The disease in the cow is ushered in by a slight fever, which, however, is usually overlooked, and the first sign is tenderness of the teats. Examined, these may be redder and hotter than normal, and at the end of two days there appear little nodules, like small peas, of a pale-red color, and increasing so that by the seventh day they may measure three-fourths of an inch to 1 inch in diameter. The yield of milk diminishes, and when heated it coagulates slightly. From the seventh to the tenth day the eruption forms into a blister, with raised margins and a depression in the center, and from which the whole of the liquid can not be drawn by a single puncture. The blister, in other words, is chambered, and each chamber must be opened to evacuate the whole of the contents. If the pock forms on a surface where there is thick hair it does not rise as a blister, but oozes out a straw-colored fluid which concretes on the hairs in an amber-colored mass. In one or two days after the pock is full it becomes yellow from contained pus and then dries into a brownish-yellow scab, which finally falls, leaving one or more distinct pits in the skin. Upon the teats, however, this regular course is rarely seen; the vesicles are burst by the hands of the milker as soon as liquid is formed, and as they continue to suffer at each milking they form raw, angry sores, scab
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