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the milk of tuberculous cows, which was virulent when injected by itself into animals, was innocuous when diluted with 40 to 100 times its volume of healthy milk. This fact is hardly to be relied upon in practice, unless the proportion of reacting to healthy cows is positively known. It has also been claimed in the centrifugal separation of cream from milk[96] that by far the larger number of tubercle bacilli were thrown out with the separator slime. Moore[97] has shown that the tubercle bacilli in an artificially infected milk might be reduced in this way, so as to be no longer microscopically demonstrable, yet the purification was not complete enough to prevent the infection of animals inoculated with the milk. Another way to exclude all possibility of tubercular infection in milk supplies is to reject all milk from reacting animals. This method is often followed where pasteurization or sterilization is not desired. In dairies where the keeping quality is dependent upon the exclusion of bacteria by stringent conditions as to milking and handling ("sanitary" or "hygienic" milk), the tuberculin test is frequently used as a basis to insure healthy milk. ~Foot and mouth disease.~ The wide-spread extension of this disease throughout Europe in recent years has given abundant opportunity to show that while it is distinctively an animal malady, it is also transmissible to man, although the disease is rarely fatal. The causal organism has not been determined with certainty, but it has been shown that the milk of affected animals possesses infectious properties[98] although appearing unchanged in earlier phases of the disease. Hertwig showed the direct transmissibility of the disease to man by experiments made on himself and others. By ingesting milk from an affected animal, he was able to produce the symptoms of the disease, the mucous membrane of the mouth being covered with the small vesicles that characterize the malady. It has also been shown that the virus of the disease may be conveyed in butter.[99] This disease is practically unknown in this country, although widely spread in Europe. There are a number of other bovine diseases such as anthrax,[100] lockjaw,[101] and hydrophobia[102] in which it has been shown that the virus of the disease is at times to be found in the milk supply, but often the milk becomes visibly affected, so that the danger of using the same is greatly minimized. There are also a numbe
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