sciatic nerve.

"'3rd. A change in the shape of the ear in animals born of parents in
which such a change was the effect of a division of the cervical
sympathetic nerve.

"'4th. Partial closure of the eyelids in animals born of parents in
which that state of the eyelids had been caused either by the section of
the cervical sympathetic nerve or the removal of the superior cervical
ganglion.

"'5th. Exophthalmia in animals born of parents in which an injury to the
restiform body had produced that protrusion of the eyeball. This
interesting fact I have witnessed a good many times, and I have seen the
transmission of the morbid state of the eye continue through four
generations. In these animals modified by heredity, the two eyes
generally protruded, although in the parents usually only one showed
exophthalmia, the lesion having been made in most cases only on one of
the corpora restiformia.

"'6th. Haematoma and dry gangrene of the ears in animals born of parents
in which these ear-alterations had been caused by an injury to the
restiform body near the nib of the calamus.

"'7th. Absence of two toes out of the three of the hind leg, and
sometimes of the three, in animals whose parents had eaten up their hind-
leg toes which had become anaesthetic from a section of the sciatic nerve
alone, or of that nerve and also of the crural. Sometimes, instead of
complete absence of the toes, only a part of one or two or three was
missing in the young, although in the parent not only the toes but the
whole foot was absent (partly eaten off, partly destroyed by
inflammation, ulceration, or gangrene).

"'8th. Appearance of various morbid states of the skin and hair of the
neck and face in animals born of parents having had similar alterations
in the same parts, as effects of an injury to the sciatic nerve.'

"It should be especially observed that Brown-Sequard has bred during
thirty years many thousand guinea-pigs from animals which had not been
operated upon, and not one of these manifested the epileptic tendency.
Nor has he ever seen a guinea-pig born without toes, which was not the
offspring of parents which had gnawed off their own toes owing to the
sciatic nerve having been divided. Of this latter fact thirteen
instances were carefully recorded, and a greater number were seen; yet
Brown-Sequard speaks of such cases as one of the rarer forms of
inheritance. It is a still more interesting fact, 'that the sciatic
n