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of headache is that which so very frequently, indeed almost invariably, occurs in the early stage of a fever or other acute infection, such as typhoid, pneumonia, or blood-poisoning, Here the face is red, the eyes are bloodshot and abnormally bright, the pulse is rapid and full, the headache so severe as to become the first disabling symptom in the disease,--all because this is the effect of the poison (toxin) of the disease upon the heart, the temperature, and the surface blood-vessels. Fortunately for the sufferer, this head-pain, like most others in the course of severe infections, is only preliminary, for as soon as the tissues of the body have become thoroughly saturated with the toxins, the nerves become dulled and semi-narcotized, so that they no longer respond with the pain-cry. As the patient settles down into the depression and dullness of the regular course of the fever, the headache usually subsides into little more than a sense of heaviness, or oppression and vague discomfort. Moral: It is a sign of health to be able to feel a headache, an indication that your body is still fighting vigorously against the enemy, whether traitor within or foe without. On the other hand, many of our most agonizing, and particularly our most persistent and obstinate headaches, occur in individuals who are markedly anaemic, with a low, weak pulse, poor circulation, blanched lips, and dull, lackluster eyes. The one and only thing in common between these two classes of "head-achers" is that their blood and tissues are loaded with poisons. Whether produced by invading germs or by starvation and malnutrition of the body-tissues makes no difference to the headache nerves. Their business, like good watchdogs, is to bark every time they smell danger of any sort, whether it be bears or book-agents. One of the most valuable services rendered us by our priceless heads is aching. This view of the nature of headache explains at once why it is so extraordinarily frequent and so extraordinarily varied in causation. It is not too much to say that _any_ influence that injuriously affects the body may cause a headache. It would, of course, be idle even to attempt to enumerate the different causes and kinds of this pain, as it would involve a review of the entire environment of the human species, internal and external. It makes not the slightest difference how the poison gets into the blood, or where it starts. A piece of tainted meat or
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