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observed on this head. 11th. What sort of scars are usually left in the arms? The scar bears the shape of the original vesicle, and is slightly depressed below the surface of the surrounding skin; the surface of the scar is marked by a number of small depressions of various shapes, corresponding, I believe, with the cells in the original vesicle. 12th. Is vaccination, in hot countries, attended with feverish symptoms? and, if it is, on what day do they begin? Vaccination is, sometimes, in this country, attended with feverish symptoms; but, in the most marked cases, so far as I have seen, these symptoms have been so slight, as almost to escape common observation. I have not remarked on what day they begin. 13th. Is vaccination ever followed by any eruptions? I have seen only one case of this: an eruption appeared on the sixth day after unsuccessful vaccination; it was diffused over the whole body, and is now in progress. W. FERGUSON, _Assistant Surgeon, Royal African Corps_. N.B. The case alluded to, in the last of the above replies, was, in the first instance, papular eruption; the base of each papula being surrounded by an inflamed ring; the eruption was thickest on the thorax, and on the arms; in its progress, the eruption became pustular, the pustules being in circumference about half the usual size of the vaccine vesicle; on the twelfth day, the crusts had dropped from some of the smaller pustules; and, by the seventeenth day, they had all dropped off, leaving a mark, but not in any manner pitted; and which, I think, promises to be permanent. W.F. _Thursday, October 4th, 1827_.--At length the day arrived when I was to quit Sierra Leone, and I might say with some regret; for, during my residence there, I had been very hospitably and agreeably entertained by the principal government officers, as well as by several of the most respectable merchants; and I had found a sufficient variety of objects of interest, to yield ample occupation for the mind. I could have desired to remain sometime longer, particularly as the fine weather, and what is called the healthy season, was fast coming on, which would have afforded me more time to examine and reflect on what was of interest to the colony as well as to the mother country; but I was conscious of a feeling of still deeper regret, and of a different character from that of mere curiosity;--it was the p
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