bles the white of an egg. The excreted urine is alkaline, acrid,
exhales a strong odor of ammonia, and soon becomes exceedingly fetid.
Sometimes the urine becomes so thick that great difficulty is
experienced in expelling it from the bladder. Nocturnal emissions,
impotency, and loss of sexual desire are apt to ensue. Occasionally
there will be a spasmodic contraction of the bladder, with straining and
a sensation of scalding in the urethra, and sometimes the patient is
unable to urinate.

When ulceration occurs in the progress of the disease, as it is apt to
in its advanced stages, blood will occasionally be seen in the urine. In
the advanced stages of the disease the system becomes greatly
debilitated, emaciation supervenes, with hectic fever, nervous
irritability and, finally, death.

TREATMENT. A strict observance of the rules of hygiene is essential to a
cure. We must ascertain the cause if possible, remove it, and thus
prevent it from perpetuating the disease. The various causes and
conditions involved in different cases demand corresponding
modifications of treatment; hence, it is useless for us to attempt to
teach the non-professional how to treat this complex disease. We have
succeeded in curing many severe cases without seeing the patient, being
guided in prescribing by indications furnished by microscopical and
chemical examinations of the urine. (See Urinary Signs in Appendix.) In
fact, nearly all cases can be cured at their homes, and without a
personal examination being made. In the worst cases, we have found it
best to have our patients at our institution, where we can wash out the
bladder with soothing, healing lotions, and thus make direct
applications to the diseased parts. (SEE TESTIMONIALS.)

GRAVEL.

When the solid constituents of the urine are increased to such an extent
that they cannot be held in solution, or when abnormal substances are
secreted, they are precipitated in small crystals, which, if minute, are
called _gravel_. Another cause of the precipitation of these salts is a
stricture of the urinary canal which, by interfering with the free
expulsion of all the fluid from the bladder, results in the retention of
a portion, which gradually undergoes decomposition. Salts from the urine
are thus precipitated in the same way that they are thrown down in urine
which is allowed to stand in a vessel. Any one can illustrate this, by
allowing a small quantity of the urinary secretion to stand