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eed from its oxygen it takes a purple hue; hence the widely different appearance of arterial and venous blood, which so puzzled the early physiologists. This proof of the vitally important role played by the red-blood corpuscles led, naturally, to renewed studies of these infinitesimal bodies. It was found that they may vary greatly in number at different periods in the life of the same individual, proving that they may be both developed and destroyed in the adult organism. Indeed, extended observations left no reason to doubt that the process of corpuscle formation and destruction may be a perfectly normal one--that, in short, every red-blood corpuscle runs its course and dies like any more elaborate organism. They are formed constantly in the red marrow of bones, and are destroyed in the liver, where they contribute to the formation of the coloring matter of the bile. Whether there are other seats of such manufacture and destruction of the corpuscles is not yet fully determined. Nor are histologists agreed as to whether the red-blood corpuscles themselves are to be regarded as true cells, or merely as fragments of cells budded out from a true cell for a special purpose; but in either case there is not the slightest doubt that the chief function of the red corpuscle is to carry oxygen. If the oxygen is taken to the ultimate cells before combining with the combustibles it is to consume, it goes without saying that these combustibles themselves must be carried there also. Nor could it be in doubt that the chiefest of these ultimate tissues, as regards, quantity of fuel required, are the muscles. A general and comprehensive view of the organism includes, then, digestive apparatus and lungs as the channels of fuel-supply; blood and lymph channels as the transportation system; and muscle cells, united into muscle fibres, as the consumption furnaces, where fuel is burned and energy transformed and rendered available for the purposes of the organism, supplemented by a set of excretory organs, through which the waste products--the ashes--are eliminated from the system. But there remain, broadly speaking, two other sets of organs whose size demonstrates their importance in the economy of the organism, yet whose functions are not accounted for in this synopsis. These are those glandlike organs, such as the spleen, which have no ducts and produce no visible secretions, and the nervous mechanism, whose central organs are the
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