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d many are astounded at the ease with which they can express their thoughts, and at the acuteness of their judgment in matters which, when they are perfectly sober, with difficulty reach their minds; and then afterwards they are ashamed at their mistakes." The action of opium in small doses is also to some extent aphrodisiacal; it slightly stimulates both the brain and the spinal cord, and has sensory effects on the skin like alcohol; these effects are favored by the state of agreeable dreaminess it produces. In the seventeenth century Venette (_La Generation de l'Homme_, Part II, Chapter V) strongly recommended small doses of opium, then little known, for this purpose; he had himself, he says, in illness experienced its joys, "a shadow of those of heaven." In India opium (as well as cannabis indica) has long been a not uncommon aphrodisiac; it is specially used to diminish local sensibility, delaying the orgasm and thus prolonging the sexual act. (W.D. Sutherland, "De Impotentia," _Indian Medical Gazette_, January, 1900). Its more direct and stimulating influence on the sexual emotions seems indicated by the statement that prostitutes are found standing outside the opium-smoking dens of Bombay, but not outside the neighboring liquor shops. (G.C. Lucas, _Lancet_, February 2, 1884.) Like alcohol, opium seems to have a marked aphrodisiacal effect on women. The case is recorded of a mentally deranged girl, with no nymphomania though she masturbated, who on taking small doses of opium at once showed signs of nymphomania, following men about, etc. (_American Journal Obstetrics_, May, 1901, p. 74.) It may well be believed that opium acts beneficially in men when the ejaculatory centers are weak but irritable; but its actions are too widespread over the organism to make it in any degree a valuable aphrodisiac. Various other drugs have more or less reputation as aphrodisiacs; thus bromide of gold, a nervous and glandular stimulant, is said to have as one of its effects a heightening of sexual feeling. Yohimbin, an alkaloid derived from the West African Yohimbehe tree, has obtained considerable repute during recent years in the treatment of impotence; in some cases (see, e.g., Toff's results, summarized in _British Medical Journal_, February 18, 1905) it has produced good results,
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