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+been indurated+ and can be felt to be +knotty+ and +hard+. The spinal marrow is very sensitive throughout its whole extent; the cerebellum is the seat of a +dull+ and +heavy pain+, and there is a feeling of pressure upon the brain. Cerebral congestion now and then occurs. This stage of the disease is frequently accompanied by +Bronchitis+ or a continued +Catarrh+, also by disease of the +rectum+ and all the +tissues near the generative organs+. It is hardly necessary to say that the functions of the nervous system are completely deranged, indeed, +nervous twitchings+ of the +eyelids+, +head+ and +limbs+ are the consequences of +Spermatorrhoea+. He is finally either hurried to a premature grave by consumption, epilepsy or apoplexy; or insanity, taking the hopeless form of dementia, has removed him from his home to the madhouse. It is safe to say that of all the cases of incurable insanity, a large majority are caused by Spermatorrhoea. Many, owing to +sheer neglect+ or to +false notions of delicacy+, delay seeking for proper medical relief until they are almost destroyed, and body and mind are nearly in ruins. Pitiable the picture of one who has +reached+ this stage of the disease. The organs are still congested but +irritability+ has given away to +torpor+ and +sluggishness+. Semen drains away by day and night without provocation, these constant losses dragging the person to the very +brink of the grave+, or +standing him+ within that +melancholy shade+ where +suicide+, +insanity+ or +idiocy+ almost certainly stares him in the face. The organs are wasted almost totally away. All +strength+, +vitality+, +erectile+ and +procreative power+ have left them, and the victim is at last totally +impotent+. Of no use to themselves, a curse to their freinds, a disgrace to society, they sink from sight into an early grave or are lost to the world behind asylum doors. It is a sad and terrible picture, but true--too true--to life. The tendency of Nature in most disorders is towards cure, but +here it is towards deterioration+. There is no chance here of the evil "wearing itself out" save in madness and death on the one hand, and on the other by the salutary intervention of the most +vigorous+, +cautious+ and +enlightened treatment+, a treatment pursued in the +full light+ of the aids afforded by the great discoveries in physiological science for which the present age is happily distinguished. Fortunately for humanity, by
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