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direct determining influence in this direction, more recently another view has been put forward, among others by Halban.[47] According to this theory, the stimulus proceeding from the glands is protective merely, not formative, nor directly stimulating the growth of organs. In the fertilised ovum, it is supposed, the rudiment of sex already exists, likewise the rudiment of the reproductive gland, and the rudiments of the appropriate sexual characters. That is to say, the development of the secondary sexual characters is not determined by the presence of the reproductive gland; but the sex of the reproductive gland and the associated sexual characters are already determined by some common cause at the moment of fertilisation. But this theoretical controversy has no very important bearing on the problem with which we are especially concerned; and the influence of the reproductive gland upon the development of the secondary sexual characters is admitted as fully by Halban as it is by other writers, the only difference between the two views lying in the dispute whether the influence of the glands is of a formative or a protective nature. The influence exercised by the reproductive glands on the development of the secondary sexual characters can be adequately discussed, even though the precise way in which that influence is exerted remains in dispute. As to the general nature of the influence, two chief theories have to be considered, viz., the nervous theory and the chemical theory. According to the former, we must assume that a stimulus originates in the reproductive glands, the testicles in the male, and the ovaries in the female, and that these glands excite a kind of reflex action--that is, that the stimulus passes to the central nervous system, and thence is "reflected" to the periphery, where it promotes, either the growth of particular parts of the body, _e.g._ the beard, or the development of definite properties in certain organs, _e.g._ the characteristics of the male larynx or of the female mamma. It is possible that the reflected impulse stimulates trophic nerves. But it may be that in cases of early castration the state of affairs is similar to that which obtains when from earliest infancy one of the sense organs is wanting, as a result of which the corresponding portions of the central nervous system are found to undergo atrophy.[48] On this assumption, the manifest arrest of the development of certain organs
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