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e favorable result. The second position is equally unsupported either by experience or sound reasoning; and is contrary not only to all medical authority on this subject, but against the investigations of other scientific men who have chemically examined the constituent principles of tobacco, and who have experimented largely to ascertain with precision its natural operation on the living fibre. The lower order of animals have been selected for these experiments. Given in substance to them, it has uniformly proved fatal, even in very minute doses. When its expressed juice or essential oil has been introduced under the skin of pigeons, kittens, or rabbits, it produced violent convulsions and often instantaneous death. Does any one doubt the correctness of these experiments? He can easily satisfy himself of their accuracy, by obtaining the oil of tobacco, and applying eight or ten drops to the root of a kitten's tongue. The same deadly effects, as we have seen, uniformly attend its first application to the human system, if taken to any considerable extent. This is well understood by its consumers, who are very cautious for many weeks, and even months, how they deal with the poisonous drug. By what transformation is a plant, so deadly in its effects when first applied to the human system, afterward converted into a harmless article of diet or luxury? No substance which God has made for the common use of man, produces similar results; and if such be the fact in relation to the article in question, in this instance at least the order of nature is reversed, so that what in its nature is poisonous, becomes by habit nutritious and salutary. If this be correct reasoning--farewell to the success of temperance efforts! For _Rum_, after all, may be _convenient_ if not necessary, because its effects are not in every instance immediately fatal; and because some, by dint of habit, can sustain with slight _apparent_ injury, what to others unaccustomed to it would produce instantaneous death. The stale excuse, so often repeated by the lovers of tobacco, that they have been advised to use it by physicians, for the mitigation or removal of some bodily infirmity, may be urged with equal force and propriety by the tippler and the sot; for many, very many, have been advised by members of the Faculty, to drink the deadly draught, in some form or other, either to ease the pains of dyspepsia, to allay the horrors of _tedium vitae_, or t
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