But that which
deserves to be well observed, and which has always seemed to characterise
and distinguish this Disease from all others, is, that almost all had at
the Beginning, or in the Progress of this Distemper, very painful Buboes,
situated commonly below the Groin, sometimes in the Groin or Arm-pits, or
in the Parotide, Maxillar, or jugular Glands; as likewise Carbuncles,
especially on the Arms, Legs or Thighs, small, white, livid, black
Pustles, dispersed over all the Surface of the Body.

It was very rare to see any of the diseased of this Second Class escape,
though they supported themselves a little longer than those of the
preceding; they perished almost all with the Marks of a gangren'd
Inflammation, especially in the Brain and Thorax; and that which was most
singular is, that the stronger, fatter, fuller, and more vigorous they
were, the less we had to hope.

As to the Remedies, they bore Bleeding no better than those of the First
Class; at least if they were not blooded at the very first Instant of
their being taken Sick: It was evidently hurtful to 'em; they grew pale,
and fell even in the time of their first Bleeding, or a little while
after, into such Faintings, as could not in most of them be imputed to any
Fear, Repugnance, or Distrust, since they demanded with Earnestness to
have a Vein opened.

All Emeticks, if we except _Ipecacuanha_, were very often more hurtful
than useful; causing such fatal Irritations and Excesses in operating, as
we could neither moderate or stop.

The Catharticks that were a little strong and active, were attended with
the same Inconveniences.

Such as we prescribed in the Form of a laxative Ptisan, as well as
plentiful Draughts, that were diluting, nitrous, cooling, and gently
alexiterial, gave some Relief, but did not hinder the Return of the
Symptoms.

All Cordials and Sudorificks, if they were not soft, gentle and benign,
did nothing but promote the Progress of the inward Inflammations.

In short, if any one escaped, which was very rare, he seem'd to owe his
Cure to the external Eruptions, when they were very much raised; either
solely by the Force of Nature, or by the Assistance of Remedies, as well
internal as external, that determined the Blood to discharge on the
Surface of the Body, the noxious Ferment wherewith it was infected.

THIRD CLASS.

The Third Class contains the two preceding; seeing we have attended,
during the Course of this terrible Sicknes