others it made the Patients sick, without producing any good
Effect.--It commonly answered better, when used occasionally as a
Sudorific, than when constantly continued.

During the Use of these Remedies, it was necessary to repeat the
Purgatives from Time to Time; or to mix them occasionally with the
other Medicines, in order to carry off any corrupted Humours, or
Excrements that might be lodged In the Cavity of the Intestines; for
when this was neglected, the Patients were often seized with Sickness
and Gripes, and a more violent Purging than before:--And if at any
Time they complained of Gripes, and passed little Pieces of hardened
Excrements, it was mostly a certain Sign that a Purge was indicated;
and, on such Occasions, it generally gave Relief; and when attended
with Sickness, a Vomit was given before the Purge.--Clysters were used
as in recent Cases, where the Sick were low, or had much Pain of the
Bowels[43], or complained of a Tenesmus.

[43] On the 21st of _November_, 1759, _Hanah Meredith_, a
middle-aged Woman, was admitted into _St. George_'s Hospital
for a Flux, which she had six or seven Weeks; she had no
Fever, but complained much of Sickness and Gripes, and her
Disorder had reduced her very low. During the two first Weeks
of her being in the Hospital, she had two Vomits of
Ipecacuana and four Doses of Rhubarb; and in the Intervals
anodyne and astringent Medicines, which made no Alteration in
her Complaints. On the 2d of _December_, she told me, that
two Years before she had had a Flux for above three Months,
which had yielded to no Remedies till she was ordered
repeated Clysters, and that they had made a Cure in a short
Time. I then ordered an emollient Clyster with a drachm of
the _electuarium diascordii_, and a Scruple of the _tinctura
thebaica_, to be given twice a Day, which gave her almost
immediate Relief; and with the Assistance of some Doses of
Rhubarb, and one or two Vomits and occasional Opiates,
removed her Disorder by the Middle of _January_; though she
remained long weak, and troubled at Times with Gripes; but
these Complaints were at last got the better of by her taking
some Doses of Rhubarb, and drinking daily a Pint of Lime
Water mixed with Half a Pint of Milk.

_Sarah Spencer_, a middle-aged Woman, was admitted into _St.
George_'s Hospital the 9th of _November_, 1763, for a Flux,
whi