suded fluid derived from the
vessels. If, therefore, a part possess a great number of vessels, and
particularly if they are superficial, it will be able to furnish an
exudation, since the fluid which transudes from the blood conveys the
special product of the tissue along with it to the surface. If this is
not the case, there will be no exudation, but the whole process will be
limited to the occurrence in the real substance of the tissue of the
special changes which have been induced by the inflammatory stimulus.

In this manner, two forms of inflammation can be distinguished, the
_purely parenchymatous inflammation_, where the process runs its course
in the interior of the tissue, without our being able to detect the
presence of any free fluid which has escaped from the blood; and the
secretory (exudative) inflammation, where an increased escape of fluid
takes place from the blood, and conveys the peculiar parenchymatous
matters along with it to the surface of the organs. That there are two
kinds of inflammation is shown by the fact that they occur for the most
part in different organs. Every parenchymatous inflammation tends to
alter the histological and functional character of an organ. Every
inflammation with free exudation generally affords a certain relief to
the parts by conveying away from it a great part of the noxious matters
with which it is clogged.

_New Formations_

I at present entirely reject the blastema doctrine in its original form,
and in its place I put the _doctrine of the continuous development of
tissues out of one another_. My first doubts of the blastema doctrine
date from my researches on tubercle. I found the tubercles never
exhibited a discernible exudation; but always organised elements
unpreceded by amorphous matter. I also found that the discharge from
scrofulous glands and from inflamed lymphatic glands is not an exudation
capable of organisation but merely debris, developed from the ordinary
cells of the glands.

Until, however, the cellular nature of the body had been demonstrated,
it seemed necessary in some instances to postulate a blastema or
exudation to account for certain new formations. But the moment I could
show the universality of cells--the moment I could show that bone
corpuscles were real cells, and that connective tissues contained
cells--from that moment cellular material for the building of new
formations was apparent. In fact, the more observers increased the mor