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n invented for measuring the heat production of a man, an apparatus which is called a calorimeter or a measurer of calories. If one puts a man weighing, say, 156 pounds in the box of such an apparatus, so that he lies comfortably on a bed in complete muscular relaxation, and before his breakfast, one finds that he produces 70 calories an hour. Only in certain types of disease is there any variation from this normal, though of course the weight of the man makes a difference in his requirement for energy. If, at the same time the subject is in the box, the quantity of oxygen which he absorbs is measured and if certain other chemical analyses be carried out, one can calculate the exact amounts of protein, fat, and sugar which have been oxidized by this oxygen. Now, if one calculates how much heat ought to have been set free from the oxidation of these quantities of protein fat and carbohydrate, it is discovered that the heat which ought to have been produced is exactly that quantity which was measured as having been produced by the man. This measurement represents the _basal metabolism_ of a man at complete rest, when his oxidative activities are at their lowest ebb. The basal metabolism as measured by 70 calories per hour in the case of this individual represents the sum of the fuel needed--(1) to maintain the beating of the heart, which every minute of a man's life moves the blood or one-twentieth part of the weight of the body, in a circle through the blood-vessels; (2) to maintain the muscles of respiration that the blood may be purified in the lungs; (3) to maintain the body temperature at that constant level which is so characteristic that a slight variation signifies illness, and (4) to maintain in the living state the numerous tissues of the body. Any extraneous muscular movements are carried out in virtue of an increased oxidation of materials and the heat production rises above the level of the basal metabolism with increased muscular effort. For a long time the power for the maintenance of the human machine can be furnished by its own body fat, as is seen in cases of prolonged fasting, but usually the power is derived instead from the food-fuel which is taken. The great question in the world to-day is whether or not a sufficient quantity of food-fuel is available to support the human family. The question of calories is not an academic one, but an intensely practical one. Science strives to express itself in ma
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